DEPARTMENT OF PATHOLOGY

Sepi Mahooti, M.D.

Sepi Mahooti, M.D.

  • Associate Professor
  • Director of Cytopathology and Fine-Needle Aspiration Biopsy Service-VAMC
  • Residency Training: The Ohio State University Medical Center (Anatomic and Clinical Pathology 2004-2008)
  • Fellowship Training: Yale University School of Medicine, (Cytopathology 2008-2009)
  • Board Certifications: Anatomic, Clinical, and Cytopathology
  • CAP Certificate of Recognition for Ultrasound-Guided Fine-Needle Aspiration (2011)
  • Clinical Subspeciality: Surgical Pathology, Cytopathology, Palpation and Ultra-sound Guided Fine-Needle Aspiration Biopsy

Research Interests

  • Early cancer detection and prognostic marker discovery.
  • Elucidation of pathways leading to early tumor invasion and metastasis.
  • Proteomic (phosphoproteomic), genomic, and metabolomic stratification of Fine-needle aspiration specimen
  • Theranostic applications in Surgical Pathology and Fine-Needle Aspiration Biopsy Specimen
  • Minimization of preanalytical variables in biospecimen
  • Biobanking of Fine-Needle Aspiration Biopsy Specimen

Representative Publications

  1. Cai G, Mahooti S, Lipata FM, Chhieng D, Hui P. Diagnostic value of K-ras mutation analysis for pancreaticobiliary cytology specimens with indeterminate diagnosis. Cancer Cytopathol, 2012.
  2. Papanicolau-Sengos A, Wang-Rodriguez J, Wang HY, Lee RR, Wong A, Hansen LA, Mahooti S, Rashidi HH. Rare case of a primary non-dural central nervous system low grade B-cell lymphoma and literature review. Int J Clin Exp Pathol, 5(1), 2012.
  3. Padda MS, Milless T, Adeniran AJ, Mahooti S, Aslanian HR. Pancreatic and Gastric Plasmacytoma Presenting with Obstructive Jaundice, Diagnosed with Endoscopic Ultrasound-Guided Fine Needle Aspiration. Case Rep Gastroenterol, 4(3), 2010.
  4. Mahooti S, Porter K, Alpaugh ML, Ye Y, Xiao Y, Jones S, Barsky SH. Breast carcinomatous tumoral emboli can result from encircling lymphovasculogenesis rather than lymphovascular invasion. Oncotarget, 131(2)2010.
  5. Mahooti, S., Wakely, P.E. Jr., FNAB Cytopathology of Thymoma, Pathology Case Reviews. 11(5), 2006.
  6. Mahooti, S., Wakely, P.E. Jr., Cytopathologic Features of Olfactory Neuroblastoma. Cancer, 108(2), 2006.
  7. Mahooti, S., Graesser D., Duncan G., Mak, T., and Madri, J.A., PECAM-1 (CD31) modulates bleeding time in vivo. American Journal of Pathology, 157 (1), 2000.
  8. Graesser D., Mahooti S., Davis S., and Madri J.A., Distinct roles for matrix metalloproteinase-2 and a4 integrin in autoimmune T-cell extravasation and residency in brain parenchyma during experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 109 (2), 2000.
  9. Ilan, N., Mahooti, S., Rimm, D.L. and Madri, J.A., PECAM-1 (CD31) functions as a reservoir for and a modulator of tyrosine-phosphorylated b-catenin. Journal of Cell Science, 112 (18), 1999.
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