Eillen Tecle


Gagneux Lab
Department of Pathology, UCSDGagneux_Lab_UCSD.html

I study how sialic acids influence immune response in the female reproductive system after mating. I use both genetic and biochemical approaches, to determine how sialic acids, sialidases and siglecs (sialic acid binding Ig-like lectins) influence the survival and success of sperm in the female reproductive tract.

I study how sialic acids modulate

female immunity during reproduction



Recent integrations of mammalian Hmg retropseudogenes
Tecle E, Zielinski L, and Kass D.H. (2006)
Journal of Genetics 2006 85:179-185eillen_files/Cohen2003_Bioph.pdf


Kass D.H., Jamison N., Mayberry M.M., and Tecle E
Identification of a unique Alu-based polymorphism and its use in human population studies Gene 2007 390:146-152eillen_files/Cohen2003_Bioph_1.pdf


Tecle E, Diaz-Balzac CA, and Bülow HE 
Distinct 3-O-sulfated heparan sulfate modification patterns are required for kal-1 dependent neurite branching in a context-dependent manner in Caenorhabditis elegans
G3 2013 3:541-52.eillen_files/Cohen2003_Bioph_2.pdf


Salzberg Y, Diaz-Balzac CA, Ramirez N, Attreed M, Tecle E, Desbois M, Kaprielian 
Z, and Bülow HE
Skin-derived cues control arborization of sensory dendrites in Caenorhabditis elegans
Cell 2013 155:308-320eillen_files/Cohen2003_Bioph_3.pdf


Molecular Genetics Tutorial

I led class wide and small group tutorial sessions for the Molecular Genetics class at the Albert Einstein College of Medicine on yeast, C. elegans, Drosophila, mouse and human genetics.

Graduate Biochemistry Tutorial

I led class wide tutorial sessions for the Graduate Biochemistry I class at the Albert Einstein College of Medicine on DNA synthesis and transcription.





Tecle, E and Gagneux, P
Sugar coated sperm: unraveling the functions of the mammalian sperm glycocalyx. Molecular Reproduction and Development. In press.eillen_files/Schwarz_etal2015eLife.pdf


Detection of the dietary xenoglycan N-glycolylneuraminic acid (Neu5Gc) and anti-Neu5Gc antibodies within reproductive tracts of male and female infertility subjects.
Sroga JM, Wu DH, Ma F, Tecle E, Reynoso HS, Ressler IB, Maxwell R, Ferrari R, Whigham L, Gagneux P, Lindheim S. 2015.  Clin Obstet Gynecol Reprod Med 2015eillen_files/SrogaetalXenoglycan%26HumanInfertility2015.pdf